A composite model for DNA torsion dynamics
| dc.creator | Cadoni, M. | |
| dc.creator | De Leo, R. | |
| dc.creator | Gaeta, G. | |
| dc.date | 2006-04-12 | |
| dc.date | 2006-04-20 | |
| dc.date.accessioned | 2026-06-02T21:48:03Z | |
| dc.description | DNA torsion dynamics is essential in the transcription process; a simple model for it, in reasonable agreement with experimental observations, has been proposed by Yakushevich (Y) and developed by several authors; in this, the DNA subunits made of a nucleoside and the attached nitrogen bases are described by a single degree of freedom. In this paper we propose and investigate, both analytically and numerically, a ``composite'' version of the Y model, in which the nucleoside and the base are described by separate degrees of freedom. The model proposed here contains as a particular case the Y model and shares with it many features and results, but represents an improvement from both the conceptual and the phenomenological point of view. It provides a more realistic description of DNA and possibly a justification for the use of models which consider the DNA chain as uniform. It shows that the existence of solitons is a generic feature of the underlying nonlinear dynamics and is to a large extent independent of the detailed modelling of DNA. The model we consider supports solitonic solutions, qualitatively and quantitatively very similar to the Y solitons, in a fully realistic range of all the physical parameters characterizing the DNA. | |
| dc.description | 29 pages | |
| dc.identifier | https://arxiv.org/abs/q-bio/0604014 | |
| dc.identifier | http://arxiv.org/abs/q-bio/0604014 | |
| dc.identifier | Phys. Rev. E75 (2007), 021919 | |
| dc.identifier | doi:10.1103/PhysRevE.75.021919 | |
| dc.identifier.uri | https://demo.dspace.org/handle/10673/2606 | |
| dc.subject | Biomolecules | |
| dc.subject | Biological Physics | |
| dc.title | A composite model for DNA torsion dynamics | |
| dc.type | text |